TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0521170
Disease: Osteoporotic Fractures
Osteoporotic Fractures 		Wounds and Injuries 0.010 1.000 1 2005 2005
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0031106
Disease: Aggressive Periodontitis
Aggressive Periodontitis 		Stomatognathic Diseases 0.020 1.000 2 2014 2016
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0001342
Disease: Acute periodontitis
Acute periodontitis 		Stomatognathic Diseases 0.020 1.000 2 2014 2016
dbSNP: rs1799964
rs1799964 		0.608 0.760 6 31574531 upstream gene variant T/C snv 0.19
CUI: C0266929
Disease: Chronic Periodontitis
Chronic Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0554021
Disease: Recurrent mouth ulcers
Recurrent mouth ulcers 		Stomatognathic Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0031099
Disease: Periodontitis
Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2011 2011
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0011334
Disease: Dental caries
Dental caries 		Stomatognathic Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0001342
Disease: Acute periodontitis
Acute periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0031106
Disease: Aggressive Periodontitis
Aggressive Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0266929
Disease: Chronic Periodontitis
Chronic Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0554021
Disease: Recurrent mouth ulcers
Recurrent mouth ulcers 		Stomatognathic Diseases 0.010 1.000 1 2013 2013
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C0001342
Disease: Acute periodontitis
Acute periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2014 2014
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C0031106
Disease: Aggressive Periodontitis
Aggressive Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2014 2014
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C0266929
Disease: Chronic Periodontitis
Chronic Periodontitis 		Stomatognathic Diseases 0.010 1.000 1 2018 2018
dbSNP: rs1800629
rs1800629 		0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.070 0.857 7 2011 2019
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.720 0.667 3 2011 2019
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.030 1.000 3 2018 2019
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1799964
rs1799964 		0.608 0.760 6 31574531 upstream gene variant T/C snv 0.19
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2018 2018
dbSNP: rs1800750
rs1800750 		0.827 0.280 6 31575186 upstream gene variant G/A snv 1.6E-02
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2018 2018
dbSNP: rs3093662
rs3093662 		0.851 0.200 6 31576412 intron variant A/G snv 7.1E-02
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.700 1.000 1 2007 2007
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C3714757
Disease: Juvenile rheumatoid arthritis
Juvenile rheumatoid arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs745738344
rs745738344 		0.653 0.600 6 31576786 synonymous variant G/A snv 1.6E-05 1.4E-05
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2018 2018
dbSNP: rs361525
rs361525 		0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases 0.030 1.000 3 2018 2019